恩瑞格在中国上市没?
The therapeutic effect of dispersible tablets is worthy of recognition. Enrig dispersible tablets have three protruding ligands that bind iron with high affinity in a ratio of 2:1. Although Enriga has a very low affinity for zinc and copper, the concentrations of these trace metals in serum decreased to varying degrees after administration. Today we will find out whether Enrig is listed in China?
According to Medical Companion Travel, Deferasirox is currently on the market in China, but is not included in domestic medical insurance. If patients want to buy cheaper Deferasirox, they can choose Deferasirox sold in India or Deferasirox produced by cipla in India. The specification is 500mg*30 tablets/box, and the price is equivalent to RMB 500$. The original drug Deferasirox launched by Novartis in India is 400mg*30 tablets/box, priced at approximately RMB 700.
Currently, Indian Deferasirox is not available in the country. Patients can only purchase it through the following methods. The first method is to fly directly to an Indian hospital pharmacy to purchase it. However, I would like to remind everyone that you must go to a regular hospital in India to buy, and do not go to the wholesale market, where there is a mixed bag of good and bad, and there are countless counterfeit products. The second option is that if financial conditions do not allow or the condition is serious, patients can choose a professional overseas medical service institution [such as Medical Companion Travel] in China, and purchase drugs through this institution’s public welfare drug search method. The safety of the drugs is guaranteed and all costs are transparent.
The research screened and optimized the prescription of Enrig dispersible tablets. The disintegration time limit and 30-minute cumulative dissolution were used as inspection indicators. The dosage of diluent microcrystalline cellulose (MCC) and lactose, the mass ratio of disintegrant cross-linked povidone (PVPP), and the amount of cosolvent sodium dodecyl sulfate (SDS) were used as factors. The L9 (34) orthogonal test table was used to design the test plan. The prescription of Enrig dispersible tablets was screened and the prescription was verified. The results showed that the optimized prescription was 12.5% MCC, 27.5% lactose, 18% PVPP (internally added), and 1.0% SDS. In the verification test, Enrig dispersible tablets completely disintegrated within 120 s, with an average 30-minute cumulative dissolution of 86.0%, which has a greater advantage than ordinary tablets. It can be seen that the dissolution rate, disintegration time and other indicators of Enrig dispersible tablets prepared according to this prescription meet the requirements.
The above is the content listed in China, I hope it can help you!
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