Lemide

Lenalidomide instructions for use

Common name: Lenalidomide

Trade name: Revlimide

All names: Lenalidomide, lenalidomide, lenalimid, Revlimide, Lenalidomide , Revlimid

[Revlimid indications]

1. Multiple myeloma: Combined with dexamethasone to treat multiple myeloma patients who have received at least one therapy.

2. Myelodysplastic Syndrome: used for the treatment of patients with transfusion-dependent aplastic anemia caused by myelodysplastic syndrome with 5q deletion cytogenetic abnormalities

[Reflimid usage and dosage]

1. Multiple myeloma: Every 28 days is a cycle. From days 1 to 21, take 25 mg lenalidomide capsules every day. Take 40 mg of dexamethasone every day on days 1-4, 9-12, and 17-20 of the first four cycles, and then take 40 mg of dexamethasone every day on days 1-4 of each subsequent cycle.

2. Myelodysplastic Syndrome: The recommended starting dose is 10 mg daily.

Usage: Take orally once with warm water, and drink a large glass of warm water while taking the medicine.

[Pharmacological effects of Revlimid]

The active ingredient lenalidomide is mainly used to treat chronic myeloma and myelodysplastic syndrome (MDS) with 5q deletion. Lenalidomide is a new generation derivative of thalidomide, but it has not been found to have teratogenic properties and is 100 times more effective than thalidomide.

According to the results of phase III clinical trials, lenalidomide is currently the most effective drug in the treatment of multiple myeloma. More than half of patients can extend their survival time to more than 3 years after taking this drug. In addition, it is also the only drug that can effectively treat myelodysplastic syndrome (MDS). Clinical results have found that 64% of MDS patients no longer need blood transfusions to treat MDS after treatment with lenalidomide.

[Adverse reactions of Reflimid]

1. Thrombocytopenia. 2. Neutrophil reduction. 3. Diarrhea. 4. Itching. 5. Rash.

[Storage of Reflimid]

Seal and store in a cool and dry place.