Romiplate

Trade name: Romiplate

English name: Romiplostim

Chinese name: Recombinant romiplostim freeze-dried powder injection

Indications

Chronic idiopathic thrombocytopenia paclitaxel

Usage and dosage

Chronic idiopathic thrombocytopenia Paclitaxel

Usually, an initial dose of 1 μg/kg is administered subcutaneously in adults as Romiplostim (gene recombinant). After the administration is started, the platelet count is increased, and the dose is increased or decreased appropriately according to the symptoms, and the drug is administered subcutaneously once a week. Additionally, the maximum dose is 10 μg/kg once weekly.

Aplastic anemia does not respond well to existing treatments

Usually, an initial dose of 10 μg/kg is administered subcutaneously to adults as romiplostim (genetically recombinant). After the administration is started, the dose should be increased or decreased appropriately according to the patient's condition and administered subcutaneously once a week. Additionally, the maximum dose is 20 μg/kg once weekly.

Packaging specifications

250μg/0.72ml

Storage method

Store at 2 to 8°C

Mechanism of action

This agent directly acts on megakaryocyte progenitor cells and exhibits platelet hematopoiesis. In addition, the agent binds to the thromboxane receptor and, through activation, promotes the growth and differentiation of megakaryocyte progenitor cells.

In addition, it acts on bone marrow hematopoietic stem cells and hematopoietic progenitor cells to promote the growth and differentiation of these cells.