度那雄胺和非那雄胺哪个更好？

Dunasteride is a dual 5α-reductase inhibitor developed by GlaxoSmithKline (GSK). It is mainly used clinically for the treatment of patients with prostatic hyperplasia (BPH). It can greatly improve various clinical symptoms of BPH and has the effect of preventing benign prostate cancer. First launched in the United States in 2003. It is currently the first and only drug that can inhibit both type I and type II 5α reductase. According to the relevant biochemical experiment results, dunasteride acts quickly and has a significant effect. Some people have always put Dunasteride and Finasteride together and said, which one of these two drugs is better?

In fact, Dunasteride and Finasteride are the same compound. Their mode of action is basically the same, by inhibiting the activity of 5α reductase and reducing the concentration of DHT. The only difference is that finasteride only inhibits type II 5α reductase, while dunasteride is not picky and accepts all type I enzymes. This is why the effect of dunasteride is much stronger than that of finasteride, because both type I enzymes and type II enzymes can combine with testosterone to generate DHT.

Dunasteride is a 5α reductase inhibitor that has a bidirectional regulatory effect and can block the conversion of testosterone into dihydrotestosterone, thereby reducing the size of the prostate and improving obstruction symptoms. Dunasteride should be taken orally, 5 mg once a day. The tablets should be swallowed whole and should not be chewed or opened as the contents may irritate the oropharyngeal mucosa. Capsules can be taken with or without food.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.