万艾可的服用禁忌和作用效果概览

Introduction: Viagra, also known as Sildenafil Citrate Tablets, is mainly used to treat male erectile dysfunction. Its main active ingredient is sildenafil, a phosphodiesterase inhibitor that stimulates the release of nitric oxide, allowing more blood to flow into the penis, thereby improving erectile dysfunction. This article mainly talks about the contraindications, effects and side effects of Viagra.

Contraindications

1. Nitrate drug users: Viagra can enhance the antihypertensive effect of nitrate drugs. Patients taking any form of nitrate drugs (including short-acting or long-acting nitroglycerin) are prohibited from taking Viagra because it may cause blood pressure to drop sharply to dangerous levels.

2. Allergy to ingredients: Patients known to be allergic to Viagra or any ingredient in this product are prohibited from taking this product.

3. Patients with cardiovascular disease: Patients with a history of cardiovascular disease, especially those with severe heart disease, should avoid using Viagra because of possible heart risks.

4. Patients with hypotension: Since Viagra has a certain antihypertensive effect, patients with hypotension may cause low blood pressure when taking it.

Pregnant and lactating women: Viagra is not suitable for pregnant and lactating women.

5. Children: Viagra is prohibited for children.

6. Users of alpha-blockers: Be cautious when using PDE5 inhibitors and alpha-blockers together, because both types of drugs have the effect of lowering blood pressure and may have additive effects, leading to hypotension symptoms.

7. People with severe liver and kidney function impairment: Since severe liver and kidney function impairment may affect the metabolism and excretion of the drug, the dose may need to be adjusted or use may be avoided.

8. Guanylate cyclase agonists: Viagra cannot be taken simultaneously with guanylate cyclase agonists to avoid causing symptomatic hypotension.

9. Protease inhibitor Ritonavir: Viagra cannot be taken at the same time as drugs containing the protease inhibitor Ritonavir to avoid increasing Viagra's blood pressure concentration and causing adverse reactions.

Effects

Vagra works by inhibiting the activity of phosphodiesterase 5 (PDE5), relaxing vascular smooth muscles and increasing blood flow in the cavernous body, thereby helping men achieve and maintain normal erectile function under sexual stimulation. Viagra can increase the release of nitric oxide in the corpus cavernosum of the penis, further causing smooth muscle relaxation and blood flow into the penile tissue, triggering an erection. This effect usually appears within 30 minutes to 1 hour after taking it, and the effects can last for several hours.

Side Effects

The most common side effects of Viagra include headache, flushing, indigestion, abnormal vision, nasal congestion, back pain, muscle pain, etc. It also affects the eyes. If you experience sudden vision loss in one or both eyes, you should stop using this drug immediately. If symptoms such as angina, dizziness, and nausea occur when sexual activity begins, sexual activity needs to be discontinued. Long-term use of Viagra may cause the body to become dependent on the drug, which may result in the patient's inability to achieve normal erections and permanent impotence. Please consult your doctor or pharmacist for specific medication and side effects. When taking any medication, follow your doctor's advice and the instructions on the medication package insert.