Insect Killer-Ivermectin Tablets
Ivermectin (IVM) is the most well-known drug among macrolide antiparasitic drugs. It is a derivative of avermectin. It is a new antibiotic anthelmintic drug with the best development effect so far. It has the characteristics of broad spectrum, high efficiency, low toxicity and high safety. It is a white crystalline powder, easily soluble in methyl ethyl ketone, propylene glycol, and polypropylene glycol, but insoluble in water. It has the effect of effectively preventing and killing nematodes and arthropods in livestock such as cattle and sheep. Its preventive and therapeutic effects are excellent.
The mechanism of action of Ivermectin in preventing and treating parasites is that Ivermectin can bind to glutamate receptors, triggering the influx of chloride, causing hypersensitivity of the parasite's nerves, hindering the initiation or conduction of normal action potentials, leading to paralysis and death of the target parasite. Ivermectin is the most popular antiparasitic drug worldwide.
Ivermectin has a good repellent effect on internal and external parasites, especially arthropod insects and internal nematodes. It is mainly used to expel gastrointestinal nematodes, lungworms and external parasites. Its mechanism of action is to promote the release of r-aminobutyric acid (GABA) from the presynaptic nerve, thereby opening the GABA-mediated chloride ion channel. The inflow of chloride ions reduces the cell membrane impedance and causes a slight super-supercharge of the resting potential of the postsynaptic membrane, thereby interfering with the signal transmission between neuromuscles, causing relaxation and paralysis of the insect body, leading to the death of the insect body or being excreted from the body.
Multiple experimental results show that ivermectin has a very significant effect on parasites and nematodes in the body. It does not have any toxic or side effects when used at the prescribed dose, indicating that ivermectin is a safe, broad-spectrum, and efficient drug for killing internal and external parasites. In spring and autumn every year, before moving to another farm or feeding in a shed, ivermectin is used to kill parasites in a preventive amount, which can effectively control the occurrence of large-scale parasitic diseases.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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