阿考替胺多少钱一盒?在哪里购买?

Acotiamide is a new drug for the treatment of functional dyspepsia. Its price, purchase channels and pharmacological properties are the focus of patients. Understanding the market price, formal access routes, and metabolic processes of drugs is of great significance to the rational use of drugs. This article will provide detailed guidance from these three aspects.

How much does a box of acotiamide cost?

The market price varies depending on the production area and specifications. Japan, as a major producing country, has representative pricing.

Japanese market price

The price of acotiamide sold in Japan is relatively stable. A standard package of 100mg*100 tablets sells for about US$50. The price is for reference only.

Price in other regions

The price purchased through cross-border channels is usually higher, and may reach 60-70 US dollars for the same specifications. The main additional costs come from international transportation and customs costs. The price of authorized production versions in some Asian countries is slightly lower, about US$45-55.

The price difference is mainly reflected in transportation costs and regional pricing policies. The quality and efficacy of drugs are basically consistent. It is recommended that patients choose purchase channels based on actual needs.

Where to buy acotiamide

To obtain acotiamide from formal channels, you need to understand its listing status in different regions and choose legal and reliable purchase channels.

Purchase in Japan

In Japan, patients can purchase it at authorized pharmacies with a prescription from a local doctor. Large chain pharmacies are selling it to ensure the quality of the medicine.

Cross-border purchase methods

For overseas patients, they can obtain it through the following methods: entrusting relatives and friends in Japan to purchase, choosing a regular cross-border drug platform, or going through the special import procedures of international hospitals. All channels require a complete prescription certificate.

When purchasing, you should check the integrity of drug packaging, production date, approval number and other information, and reject drugs from unknown sources.

Pharmacokinetics of acotiamide

Understanding the absorption, distribution, metabolism and excretion process of acotiamide in the body will help optimize the medication regimen and improve the therapeutic effect.

Absorption and Distribution

It is rapidly absorbed after oral administration, with a bioavailability of approximately 60%. The peak plasma concentration occurs 2-3 hours after administration. The binding rate of the drug to plasma proteins is as high as 95%, and it is widely distributed in tissues throughout the body.

Metabolism and Excretion

Mainly metabolized in the liver through CYP3A4 enzyme to generate a variety of active metabolites. About 70% is excreted through bile and 30% is excreted through kidneys. The elimination half-life is about 15 hours.

Patients with hepatic and renal insufficiency may need dose adjustment, and potential drug interactions should be noted when coadministered with CYP3A4 inhibitors or inducers.