How many specifications does Nadimedin have? How much does it cost?

Author: Medicalhalo

Release time: 2025-10-19 11:44:20

Naldimedine is a drug used to treat opioid-induced constipation in adults with chronic non-cancer pain. It is produced by Shionogi Pharmaceuticals of Japan. Currently, the drug is available in two specifications: 0.2mg*50 tablets and 0.2mg*14 tablets, priced at US$520 and US$173 respectively. Nadimedine has not yet been launched in China, nor has it been included in medical insurance. Patients must purchase it through formal channels.

Nadimedine is available in several specifications

As a drug specifically used to treat constipation caused by opioids, it is currently produced by Japan's Shionogi Pharmaceuticals and has two specifications. The two specifications are completely identical in terms of drug ingredients and dosage forms, but differ in packaging quantity to meet the needs of different patients.

0.2mg*50 tablets specification

Each box of this specification of Nadimedine contains 50 tablets, and the dosage of each tablet is 0.2mg. The tablets are yellow, round, film-coated tablets with the Shionogi mark and identification code 222 printed on one side and the identification code 0.2 on the other side. This specification is suitable for patients who need long-term medication and can reduce the trouble of frequent drug purchases.

0.2mg*14 tablets specification

Each box of this specification of Nadimedine contains 14 tablets, and the dosage of each tablet is also 0.2mg. Its properties and appearance are completely consistent with the 50-piece specification. This specification is suitable for patients who need to take medication for a short period of time or who need to trial drugs, and provides more flexible medication options.

Whether it is 50 tablets or 14 tablets, the dosage form and ingredients of Nadimedine are the same, and patients can choose the appropriate specification according to their own needs.

How much does Nadimedin cost for different specifications?

The price of Nadimedin varies depending on the specifications. Currently, the prices of two specifications of Nadimet produced by Japan's Shionogi Pharmaceutical are US$520 and US$173 respectively. Below is a detailed introduction to the prices of these two specifications.

Price of 0.2mg*50 tablets

The price of this specification of Nadime is US$520 per box. For patients who require long-term medication, although the single purchase cost is higher, the price per tablet is relatively low, making it more economical.

The price of 0.2mg*14 tablets

The price of this specification of Nadimax is US$173 per box. Although the price of a single box is low, the price of each tablet is slightly higher than that of 50 tablets, which is suitable for patients with short-term medication or trial needs.

Nadimedine has not yet been launched in China, nor has it been included in medical insurance. Patients must purchase it through formal medical service institutions or cross-border e-commerce platforms. When purchasing, they must pay attention to the authenticity and production date of the drug.

How safe is Naldimedine?

Naldimedine has a good effect in treating constipation caused by opioids, but its safety still needs to be paid attention to during use.

Common adverse reactions

The most common adverse reactions of nadimedine include abdominal pain, diarrhea, nausea and gastroenteritis. These symptoms are usually mild, but if severe, persistent, or worsening abdominal pain occurs, the medication should be stopped and medical attention should be sought immediately.

Drug Safety for Special Populations

Pregnant women, lactating women, children, the elderly and patients with liver damage should be particularly cautious when using Nadimedine. Pregnant and lactating women should evaluate the risks and benefits under the guidance of a doctor, and patients with severe liver damage should avoid using this drug.