How many versions of Nadimedin are there? How much do they cost?

Naldimedine is a drug used to treat opioid-induced constipation in adults with chronic non-cancer pain. It is produced by Shionogi Pharmaceuticals of Japan. Currently, there are two main versions on the market, namely 0.2mg*50 tablets and 0.2mg*14 tablets, with prices of US$520 and US$173 respectively. Nadimedine has not yet been launched in China, nor has it been included in medical insurance. Patients must purchase it through formal channels.

What versions of Nadimedine are there

It is a drug specially used to treat constipation caused by opioids. It is currently produced by Japan's Shionogi Pharmaceuticals and is mainly divided into two specifications. The two versions are identical in dosage form and properties, but differ in packaging quantity to meet the needs of different patients.

0.2mg*50 tablet version

This version of Nadimedine contains 50 tablets per box, and the dosage of each tablet is 0.2mg. The tablets are yellow, round, film-coated tablets with the Shionogi mark and identification code 222 printed on one side and the identification code 0.2 on the other side. This specification is suitable for patients who need long-term medication and can reduce the trouble of frequent drug purchases.

0.2mg*14 tablet version

This version of Nadimedine contains 14 tablets per box, and the dosage of each tablet is also 0.2mg. Its properties and appearance are exactly the same as the 50-piece version. This specification is suitable for patients who need to take medication for a short period of time or who need to trial drugs, and provides more flexible medication options.

Whether it is a 50-tablet or 14-tablet version, the dosage form and ingredients of Nadimedine are the same, and patients can choose the appropriate specifications according to their own needs.

How much do different versions of Nadimed cost?

The price of Nadimed varies depending on the specifications. Currently, the prices of two specifications of Nadimet produced by Japan's Shionogi Pharmaceutical are US$520 and US$173 respectively. Below is a detailed introduction to the prices of these two specifications.

The price of the 0.2mg*50 tablet version

The price of this specification of Nadime is US$520 per box. For patients who require long-term medication, although the single purchase cost is higher, the price per tablet is relatively low, making it more economical.

The price of the 0.2mg*14-piece version

The price of this specification of Nadimax is US$173 per box. Although the price of a single box is lower, the price of each tablet is slightly higher than the 50-piece version, which is suitable for patients with short-term medication or trial needs.

Nadimedine has not yet been launched in China, nor has it been included in medical insurance. Patients must purchase it through formal medical service institutions or cross-border e-commerce platforms. When purchasing, they must pay attention to the authenticity and production date of the drug.

Precautions for the use of naldimedine

Although naldimedine can effectively treat constipation caused by opioids, there are still some things that need to be paid attention to during use to avoid adverse reactions or drug interactions. The following are some points that require special attention when using Nadimet.

Usage and Dosage

The recommended dose of Nadimedine is 0.2 mg orally once a day, which can be taken with or without food. No adjustments to the analgesic dosing regimen are required before initiating naldimedine. If the opioid analgesic is discontinued, naldimedine should also be discontinued.

Adverse reactions

The most common adverse reactions of nadimedine include abdominal pain, diarrhea, nausea and gastroenteritis. If severe, persistent, or worsening abdominal pain occurs, discontinue the medication and seek medical attention immediately.

Usage in Special Populations

Pregnant women, lactating women, children, the elderly and patients with liver damage should be particularly cautious when using Nadimedine. Pregnant and lactating women should evaluate the risks and benefits under the guidance of a doctor, and patients with severe liver damage should avoid using this drug.

The storage of naldimedine also requires protection from light, moisture and temperature control to ensure drug stability. Patients should strictly follow medical instructions during use and monitor their physical condition regularly.