恩瑞格需要注意的事项有哪些呢？

地中海贫血患儿常会并发体内积聚过量铁质、继发性脾功能亢进、胆结石等，严重影响着孩子们的健康与生命，一定要积极治疗。而就是用于治疗地中海贫血的药物，恩瑞格主要成份为地拉罗司，主要用于因需要长期输血而引致铁质积聚的患者（如患有地中海贫血症或其他罕见的贫血症） ，适用于两岁以上儿童及成人服用。 So, what are the things that Enrig needs to pay attention to?

1: Deferasirox, the main ingredient of Enriga, may cause rashes. Although the rash usually disappears automatically without the need to adjust the dosage or stop taking the medication, some patients may have more serious conditions or may continue to occur, so the medication must be stopped in time. Two: After taking this medicine, the patient's vision or hearing may be affected. Three: This medicine should be taken 30 minutes before meals. Four: The time of taking this medicine must be the same every day, so that the effect of the medicine will be better. Patients and friends should pay more attention to these precautions. 5: It is recommended that patients with iron accumulation, such as those who require long-term blood transfusion (blood transfusion volume up to 100 ml/kg) and whose serum ferritin exceeds 1000 μg/L, are initially recommended to take 20 mg/kg of deferasirox daily according to their body weight. Depending on the serum ferritin index, patients may need to adjust or increase the dose of deferasirox, which is usually 5 mg/kg or 10 mg/kg. The dose is adjusted in units of kilograms, but the total dose should not exceed 30 mg/kg per day. VI: Gastrointestinal events: Gastrointestinal bleeding (including death) may occur; more common in patients with advanced hematological malignancies and/or elderly patients with low platelet counts; discontinue treatment for suspected gastrointestinal bleeding or ulceration. Nonfatal upper GI irritation, bleeding, and ulceration (sometimes complicated by GI perforation, including death) have been reported. Use concomitant medications with caution that may increase the risk of adverse gastrointestinal effects (eg, nonsteroidal anti-inflammatory drugs, corticosteroids, anticoagulants, oral bisphosphonates). Monitor patients closely for signs/symptoms of gastrointestinal ulceration/bleeding while taking this product.