奥贝胆酸要多少钱一盒？

(Obetix) is a farnesoid X receptor agonist that indirectly inhibits the gene expression of cytochrome 7A1 (CYP7A1) by activating the farnesoid X receptor. Since CYP7A1 is the rate-limiting enzyme in cholic acid biosynthesis, obeticholic acid can inhibit cholic acid synthesis and be used to treat primary biliary cirrhosis and non-alcoholic fatty liver disease.

Obeticholic acid (Obetix) was successfully developed by Intercept Pharmaceuticals in the United States. It is the first drug developed to treat cholestatic liver disease in 20 years. The study is for patients who have not responded adequately to or are intolerant to the old standard treatment, ursodeoxycholic acid. In a placebo-controlled phase 3 clinical trial, obeticholic acid (OCA) increased levels of two biomarkers associated with a reduced risk of liver transplantation. The composite endpoint of the clinical study was a decrease of at least 15% in alkaline phosphatase, a biomarker used to indicate the severity of liver disease, with serum alkaline phosphatase activity less than 1.67 times the upper limit of normal, and bilirubin within the normal range.

How much does a box of obeticholic acid cost?

The price of obeticholic acid (Obetix) in the United States is extremely high, 5mg-30 tablets/box, priced at US$6529.580; 10mg-30 tablets/box, priced at US$6529.580. The original version of obeticholic acid produced in the United States is expensive and most patients cannot afford it, so many patients turn to cheaper generic drugs.

The generic drug Obetix produced by Bangladesh's Becon Pharmaceuticals has been approved for marketing. The Bangladeshi version of obeticholic acid (Obetix) has been approved by government regulatory agencies for marketing and is a legal drug. Medical Companion Travel cooperates with Bangladeshi pharmaceutical companies and can directly contact pharmaceutical companies to help patients purchase genuine medicines. The Bangladeshi version of obeticholic acid is cheaper, with the market price around 2,000.