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去纤苷注射注意事项

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

Defibrotide injection precautions:

Bleeding: Defitelio may increase plasmin activity in vitro and may increase the risk of bleeding in patients with VOD after hematopoietic stem cell transplantation (HSCT). Do not initiate Defitelio treatment in patients with active bleeding. Monitor patients for signs of bleeding. If a patient develops symptoms of bleeding, discontinue use and provide treatment until bleeding stops. Concomitant use of defibrotide and systemic anticoagulation or fibrinolytic therapy (not included for routine maintenance or reopening of central venous lines) may increase the risk of bleeding. Discontinue anticoagulants and fibrinolytics before defibrotide therapy and consider delaying the use of defibrotide until the effect of the anticoagulant has diminished.

Hypersensitivity reactions: Less than 2% of patients treated with defibrotide experienced allergic reactions. These reactions include rash, urticaria, and angioedema. One case of an allergic reaction in a patient has been reported. Monitor patients for hypersensitivity reactions, especially those with past exposure. If a severe hypersensitivity reaction occurs, discontinue defibrotide, treat according to standard of care, and monitor until symptoms resolve.

It is not currently on the market in China, so it will not be included in China's medical insurance catalog to provide everyone with preferential medical insurance policies. Patients who want to purchase defibrotide can only go abroad to purchase defibrotide at their own expense. However, as we all know, the price of original drugs is very expensive, and a lot of manpower and material resources are consumed in the process of purchasing drugs, which puts huge pressure on patients. Therefore, more people choose to purchase drugs overseas to obtain the drugs they need. According to what Medical Companion Travel currently knows, the specification of defibrinoside is 200 mg, and the price is about $21,600. It is more suitable for patients to use for a long time, is high quality and low price, and saves worry and effort. The exchange rate in the market often fluctuates, and the price is not always fixed, but will change with the exchange rate. For more information about defibrotide, please contact Medical Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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