去纤维钠作用及价格

Also called defibrinoside, it was originally developed by Gentium Pharmaceuticals in Italy and was approved for marketing in the EU in October 2013. After Gentium Pharmaceuticals was acquired by Jazz Pharmaceuticals of the United States, defibrotide sodium was approved by the U.S. Food and Drug Administration (FDA) for marketing in the United States on March 30, 2016, under the trade name Defitelio.

The role of defibrinated sodium:

Defibrotide sodium is an adenosine receptor agonist with multiple effects. The adenosine A1/A2 receptors of endothelial cells are involved in the regulation of endothelial cells and the response of endothelial cells to injury. Defibrotide sodium can act on these receptors to produce a variety of downstream effects. Defibrinated sodium can also reduce the expression of cell adhesion molecules on the surface of endothelial cells, thereby reducing the adhesion of leukocytes to vascular endothelial cells and reducing the inflammatory damage of endothelial cells.

In clinical trials, defibrinated sodium also effectively improved the 100-day survival rate of patients. In one study, 42% of patients using defibrinated sodium achieved complete remission (CR), and the 100-day overall survival (os) rate after transplantation reached 32%.

Defibrinated sodium price:

Defibrotide sodium plays an obvious role in the treatment of hepatic veno-occlusive disease, and many patients are also very concerned about its price. It is understood that defibrinated sodium is not currently on the market in my country. The overseas version of defibrinated sodium is equivalent to about $22,000 in RMB. If it is inconvenient for patients to go abroad, they can consult our Medical Companion Travel Overseas Medical Consulting Service Company to learn how to purchase it.

The above is an introduction to the role and price of defibrinated sodium. Since the degree of disease of each patient is different, the time for defibrinated sodium to take effect is not exactly the same. Patients should actively cooperate with the treatment under the diagnosis of the doctor and do not blindly take medication. If you have any other questions, please consult the medical companion passenger service.

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