去纤苷国内卖多少钱？

Defibrotide sodium, also known as defibrotide and defiteli, was approved for marketing in the EU in October 2013. It is currently recognized as the most promising new drug for the treatment of hepatic veno-occlusive disease (HVOD) after hematopoietic stem cell transplantation (HSCT). Defibrotide sodium was first developed by Italy's Gentium Pharmaceuticals and was approved by the U.S. Food and Drug Administration (FDA) for marketing in the United States on March 30, 2016.

For some patients with leukemia and lymphoma, hematopoietic stem cell transplantation (HSCT) is the only hope to cure the disease and regain health. Hepatic veno-occlusive disease (HVOD) is one of the serious complications after hematopoietic stem cell transplantation (HSCT). Defibrotide is an adenosine receptor agonist with multiple effects. The adenosine A1/A2 receptors of endothelial cells are involved in the regulation of endothelial cells and the response of endothelial cells to injury. Defibrotide (defiteli) can act on these receptors to produce a variety of downstream effects.

Defibrotide is an injection that is not currently available in my country. Defibrotide has the effects of anticoagulation, promoting fibrinolysis, and promoting blood vessel formation, and has played a significant role in preventing and treating HVOD.

Since it has not yet been launched in my country, there is no domestic price for defibrotide. We learned that the current price of defibrinoside on the market is about $22,000 per box. Patients can consult the medical companion service for specific information.

Defibrotide (defiteli) is a single-stranded oligonucleotide mixture with anti-thrombotic and fibrinolytic effects. It has a good therapeutic effect on adults and children. The dose used in treatment should be based on the patient's weight. The recommended dose is 6.25 mg/kg given every 6 hours as a 2-hour intravenous infusion. Minimum usage time is 21 days. If signs and symptoms of HVOD have not resolved after 21 days, continue defibrotide until resolution of HVOD or up to a maximum of 60 days.