非布司他一盒要多少钱？

It is an anti-gout medicine. Febuxostat has a significant inhibitory effect on both oxidized and reduced XOR, so its effect of reducing uric acid is more powerful and lasting. Therefore, this product can be used to treat chronic hyperuricemia in gout. How much does a box of febuxostat cost?

Price of Febuxostat: It is understood that the price of Febuxostat on the domestic market is relatively expensive and is not suitable for patients to take it for a long time. What I need to tell you here is that the efficacy of Febuxostat produced by Zydus Pharmaceutical Factory in India is the same as that of the original drug. The price is indeed much lower. The specification is 80mg*30 tablets/box. Its price is about 200$. Due to the floating exchange rate, the price is different. Please consult the medical companion for the specific price!

The currently recommended application method of febuxostat: the initial dose is 40 mg/d. If the blood uric acid has not reached ≤6.0 mg/dl after 2 weeks, the dose will be increased to 80 mg/d.

Febuxostat drug interactions:

1. Naproxen and other glucuronidation inhibitors:

Febuxostat metabolism is dependent on glucuronosyltransferase. Drugs that inhibit glucuronidation, such as NSAIDs and probenecid, may theoretically affect the elimination of febuxostat. In healthy subjects, concurrent use of febuxostat and naproxen 250 mg twice daily was associated with increased febuxostat exposure. Febuxostat can be used concurrently with naproxen, and no dose adjustment of febuxostat or naproxen is required.

2. Glucuronidation inducer:

Potent inducers of glucuronosyltransferase may result in increased metabolism and reduced efficacy of the drug. Therefore, it is recommended to monitor serum uric acid 1 to 2 weeks after starting administration of a potent inducer of glucuronidation. Conversely, discontinuation of treatment with an inducer may result in increased plasma levels of febuxostat.

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