非布司他去哪买的到呢？

It is suitable for the long-term treatment of hyperuricemia combined with gout, including gout patients with increased uric acid production and decreased renal clearance. It is especially suitable for gout patients who cannot tolerate or have contraindications for allopurinol and whose uric acid cannot reach the target after allopurinol treatment. However, febuxostat is not recommended for the treatment of asymptomatic hyperuricemia. Today we will learn about where to buy febuxostat?

Purchase channels for Febuxostat: Febuxostat is already on the market in China, and patients can buy it in major domestic hospitals with a prescription issued by a doctor. However, according to current understanding, the febuxostat used by gout patients on the market is the Indian generic version. The reason is that the price of the generic version of febuxostat is much lower than the domestic price. Indian generic drugs are not available on the domestic market, but they can still be purchased through formal channels. Domestic patients who want to buy high-quality and low-priced Indian Febuxostat can contact domestic medical institutions to purchase it. With the help of the medical institutions, they sign a guarantee contract, transfer the money directly to India without handling the drugs and money, and then deliver Febuxostat to the patients by direct mail from India.

The price of febuxostat in China is higher than that in India, about $1,500 per box. Febuxostat produced by Zydus Pharmaceutical Factory in India has the same efficacy as the original drug, but the price is indeed much lower. The specification is 80mg*30 tablets/box. Its price is about 200$. Due to exchange rate fluctuations, the price varies.

Febuxostat is absorbed in the intestine after oral administration, with a bioavailability of 47%, a blood and plasma protein binding rate of 99.2%, and is mainly metabolized in the liver, with a half-life of 5 to 8 hours. It is metabolized in the liver into inactive substances, 49% is excreted through the kidneys, and 45% is excreted through the feces, which is a dual-channel excretion drug. Therefore, the dosage is small and it is not completely dependent on renal excretion, so patients with gout who have mild to moderate renal insufficiency do not need to adjust the dosage when using it. However, gout patients with abnormal liver function need to use it with caution.

Some patients may experience abnormal liver function after taking febuxostat, so liver function should be monitored regularly. If transaminase increases by more than three times the normal value, the drug should be discontinued. Some patients may also experience nausea, diarrhea, rash and other side effects, and some may also experience angioedema, acute renal failure, acute hemoglobin reduction, etc.

The above is the content of purchasing channels, I hope it can help you!