非布司他是治什么的？

What does it treat? Febuxostat tablets are a drug with a relatively significant effect in treating gout. It is commonly used in clinical treatment and the safety of the drug is relatively high.

The therapeutic principle of Febuxostat tablets is the chemical name: 2-[(3-cyano-4-isobutoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid. Molecular formula: C16H16N2O3S. Molecular weight: 316.37. It is white or off-white tablets. It is suitable for the long-term treatment of hyperuricemia in patients with gout. The pharmacological effect of Youlitong Febuxostat Tablets is that Febuxostat is a xanthine oxidase inhibitor and achieves therapeutic effects by reducing serum uric acid. Febuxostat tablets ingredient Febuxostat is a xanthine oxidase inhibitor, which mainly reduces serum uric acid concentration by inhibiting uric acid synthesis. Febuxostat does not inhibit other enzymes involved in purine and pyrimidine synthesis and metabolism at conventional therapeutic concentrations.

The recommended oral dose of febuxostat tablets is 40 mg or 80 mg once daily. The recommended starting dose of febuxostat tablets is 40 mg once daily. If the blood uric acid level is still not less than 6 mg/dl (approximately 360 µmol/L) after 2 weeks, it is recommended that the dose be increased to 80 mg once a day. Food and antacid effects do not need to be considered when administering the drug. Special populations: Patients with hepatic impairment: Patients with mild or moderate hepatic impairment (Child-Pugh A, B) do not need to adjust the dose. The efficacy and safety of febuxostat in patients with severe hepatic insufficiency (Child-Pugh class C) have not been studied, so febuxostat should be used with caution in these patients.

In the early stages of taking it, gout attacks may occur because changes in blood uric acid levels cause tissue-deposited urate to be mobilized. To prevent gout attacks during the initial stages of taking febuxostat, it is recommended to take NSAIDs or colchicine at the same time. The benefits of preventive treatment can last up to 6 months. If gout attacks during treatment with febuxostat, there is no need to interrupt the medication. Gout should be treated accordingly based on the patient's individual circumstances. If serious adverse reactions occur, you should communicate with the attending doctor in time and go to the hospital for symptomatic treatment.