非布索坦贵吗？

Gout is a common and complex type of arthritis. People of all ages may suffer from gout. Gout patients often experience sudden joint pain at night. The pain is quite high and feels like a big toe being burned. If not treated in time, the consequences of delay will be that the pain will become stronger and more unbearable. And it can also endanger other normal functions of the body. Also called febuxostat, it is an anti-gout drug. Because febuxostat has a significant inhibitory effect on both oxidized and reduced XOR, its uric acid-lowering effect is more powerful and long-lasting. Therefore, febuxostat can be used to treat chronic hyperuricemia in gout. On September 4, 2018, the domestic CFDA officially approved the listing of febuxostat. The domestic febuxostat tablets are also called fibril.

The essential cause of gout is the increase in uric acid levels in the body, which causes the deposition of urate in the joints and kidneys. Generally speaking, the main causes of gout include: ① Dietary reasons: After eating too much meat and seafood, and drinking too much beer, the body's uric acid level rises, which may cause urate deposition; ② Obesity: The consequence of obesity is an increase in uric acid in the body, and the kidneys cannot completely remove excess uric acid; ③ Taking certain drugs: These drugs can cause the body's uric acid levels to increase; ④ Family history: If a family member suffers from gout, your probability of getting the disease will also be greatly increased.

Febuxostat is a new non-purine xanthine oxidase (XO) selective inhibitor that works by reducing blood urate concentration. It is completely absorbed after oral administration and has a high utilization rate. Food and antacids have no significant effect on its absorption. Unlike allopurinol, its structure is a non-purine analogue, so it is selective in inhibiting xanthine oxidase and has little effect on other enzymes in purine or pyrimidine metabolism. This means that febuxostat is less likely to be affected by other factors and has a stable effect.

The domestic price of febuxostat is 10 yuan per tablet, 40mg/tablet. The recommended dosage of febuxostat is 40mg/day, which means that febuxostat will cost about 300 a month. For those who do not tolerate febuxostat well, the dosage may need to be increased to 80mg/day, which means two tablets a day, which is about 600 a month. For gout, febuxostat is also a long-term consumption. In comparison, the price in India is relatively affordable: 80mg*30 tablets/box, priced at about 200$.