How much does it cost to complete a complete course of pemetinib?

Pemigatinib is a targeted drug used to treat cancers such as cholangiocarcinoma. It is currently on the market in China, but it is not yet covered by medical insurance, so patients face a high financial burden when using it. There are mainly two specifications on the market: 4.5 mg 14 tablets and 9 mg 14 tablets. The price range is roughly RMB 20,000 to RMB 50,000 per box. The specific price varies depending on different supply channels and regions.

A complete course of medication is usually 28 days (i.e. one box of medicine). The length of the course of treatment will vary depending on the doctor's dosage and the patient's specific conditions. Taking a general course of treatment as an example, patients need to take it continuously for several months. If the course of treatment is 6 months, the cost will reach hundreds of thousands or even more than 200,000 yuan, which is a large expense for most patients.

In overseas markets, the price of pemetinib is more expensive. Taking 13.5mg*14 tablets as an example, the price per box may exceed RMB 70,000. Exchange rate and market fluctuations will have a certain impact on the price. Therefore, many patients and families will consider purchasing generic drugs through overseas channels to reduce financial pressure.
Among the generic drugs, pemetinib 4.5mg*14 tablets produced by Lucius Pharmaceuticals in Laos is priced at only more than 700 yuan, which is a significant price drop compared to the original drug. Although the ingredients of generic drugs are basically the same as those of original drugs, patients should ensure the quality and formal channels of the drug when choosing, and use the drug rationally based on the doctor's advice to ensure therapeutic effect and safety.
Reference: https://go.drugbank.com/drugs/