How to buy regular Mobosetinib/Mobosetinib

Mobocertinib is the world's first oral targeted drug approved for EGFR Exon20 insertion mutation non-small cell lung cancer (NSCLC) in 2021 It was approved for marketing by the U.S. Food and Drug Administration (FDA) in 2016, and entered the NCCN Pathway recommended regimen; the European Medicines Agency (EMA) was officially approved to enter the European market in 2023, and its efficacy is significantly better than traditional chemotherapy according to PFS and OS indicators. In China, the drug was introduced by a domestic manufacturer in early 2023 and completed NMPA approval, but was subsequently removed from the shelves after being briefly marketed for some reasons. At present, there is still no clear time for re-entering the market in China.

In terms of market dynamics, the clinical version of mobosetinib is currently available in Hong Kong and other places. The specification is 40 mg × 30 tablets, and the price is approximately RMB 7,000 per box. It should be noted that this sales channel has a certain degree of legal and regulatory grayscale. Drug buyers should ensure that the drugs are from formal channels and come with approval documents and quality traceability information. It is recommended that personal purchasing agents go through pharmacies with Hong Kong registered wholesale qualifications, or sign medical orders with well-qualified overseas hospitals through international medical platforms to ensure compliance with drug purchases.

Since the adjuvant efficacy study of mobosetinib is mainly based on EGFR Exon20 mutated advanced lung cancer patients, it is contraindicated when it is not approved for use in other tumor types (such as liver cancer, colorectal cancer, etc.). On the whole, the contraindications of mobosertinib are strict and scientific, which not only clearly point to specific molecular targets, but also avoid the risk of possible serious adverse reactions. It is a typical anti-cancer drug development model of "target limitation, precise adaptation, and process monitoring" in the era of precision medicine.

Reference materials:https://en.wikipedia.org/wiki/Mobocertinib