How much does a box of pemetinib cost? Is it reimbursable?

Pemigatinib, also known as pemetinib (Pemigatinib), is a targeted drug developed for specific tumor gene mutations (such as FGFR2 fusion or rearrangement). It is mainly used to treat locally advanced or metastatic cholangiocarcinoma and other tumor types. This drug has been approved for marketing in China under the name of "pemetinib tablets". However, due to the short period of inclusion, it has not yet been included in the national medical insurance directory. This also means that patients need to bear the cost of the drug out of their own pocket when taking the drug, and the treatment burden is relatively large.

In the domestic market, the common specifications of pemetinib include 4.5mg 14 tablets and 9mg 14 tablets. The selling price varies according to the specifications and supply channels. According to current public market information, the price of a box of pemetinib is roughly between 2 yuan and 5 yuan. For example, the 9mg specification is often closer to the upper limit due to its higher dosage and shorter medication period, while the 4.5mg specification is relatively cheaper. This price puts financial pressure on many patients who need to take it long-term and cannot be ignored.

For patients who want to reduce treatment costs, there are also abundant choices in overseas channels. Currently, in the markets of European and American countries, the price of the original drug pemetinib is higher. For example, the specifications of 13.5mg*14 tablets in the United States or Europe may cost up to 7 or more per box, which is mainly affected by exchange rates, import taxes, and different medical insurance systems in different countries. In comparison, these prices are not advantageous.

However, it is worth mentioning that there are currently generic versions of pemetinib in overseas markets, especially those produced by Laos Lucius Pharmaceutical Company. Its price of 4.5mg*14 tablets is about RMB 700. The price is much lower than that of the original drug, and the active ingredients are basically the same. Therefore, it is highly cost-effective for patients with limited economic conditions or long-term medication. When patients choose generic drugs, it is recommended that they purchase them through formal channels and use them under the guidance of a doctor to ensure therapeutic effects and medication safety.

Reference materials:https://go.drugbank.com/drugs/DB15102