The underlying reasons for the high price of Trientine

Trientine(Trientine), as a drug used to treat Wilson's disease, has long maintained a high price worldwide, especially in the Chinese market. The high price of this drug is mainly affected by the following underlying reasons.

First of all, trientine hydrochloride is an imported drug, and its original drug is not produced in China. This means that the production, transportation and sale of drugs involve multiple links, each of which increases the final price of the drug. In the process of moving drugs from overseas manufacturers to the Chinese market, they face multiple expenses including production costs, transportation fees, tariffs, and import and export restrictions. These costs are ultimately passed on to consumers, causing drug prices to continue to rise.

Secondly, trientine hydrochloride is a specific drug for the treatment ofWilson's disease, and the market demand is relatively small. Wilson's disease is a rare genetic disorder that affects only a small number of people, so the market for drugs targeting it is smaller. Due to limited market demand, pharmaceutical companies may not be able to reduce unit drug production costs through large-scale production. In addition, the drug development and production process requires high standards of quality control and strict regulatory review, which further increases the production cost of drugs. Drugs targeted to minority patient groups often have higher prices.

Another reason is the patent protection period of trientine. Although the patent period of trientine is coming to an end, the original drug still occupies a dominant position in the market, and the production and sales of generic drugs are relatively difficult. Although generic drugs have appeared in some countries or regions, the entry of generic drugs has been greatly restricted because pharmaceutical companies have held patents for a long time. Even if generic drugs enter the market, regulatory policies, certification requirements, market access and other factors in some countries or regions have prevented the selling prices of generic drugs from significantly decreasing and still maintaining high prices.

Reference materials:https://www.cufence.com/