What is the latest price of a box of obeticholic acid in 2025?

Obeticholic acid (Obeticholic acid) is a new type of liver drug mainly used to treat primary biliary cholangitis (PBC). This disease is an autoimmune disease that mainly affects the liver, causing bile excretion disorders and liver damage. The mechanism of action of obeticholic acid is to regulate bile salt metabolism by activating farnesoid X receptor (FXR), and has anti-inflammatory and anti-fibrotic effects, which can effectively alleviate symptoms and improve patients' quality of life.

In China, obeticholic acid has not yet received marketing approval, so patients cannot purchase the drug through formal channels, nor can they enjoy the relevant protections of the medical insurance policy. This means that patients face great difficulties in finding treatment options, and there is currently a lack of clear public data on the price of this drug in the domestic market.

In overseas markets, the original drug of obeticholic acid is usually sold in tablets of 5mg and 10mg specifications. The price of 30 tablets per box may be as high as more than 20,000 yuan, and the specific price will also be affected by exchange rate fluctuations. Although the drug has shown significant efficacy in the treatment of primary biliary cholangitis, its high price prohibits many patients.

It is worth noting that as the demand for obeticholic acid increases, some generic drugs have gradually appeared in overseas markets. The ingredients of these generic drugs are similar to the original drugs and can provide similar therapeutic effects. Suppliers include ASEAN Pharmaceuticals of Laos, Beacon Pharmaceuticals of Bangladesh, Mylan Pharmaceuticals of India, etc. The prices of these generic drugs are relatively affordable, usually ranging from a few hundred to a thousand yuan, although prices will vary due to exchange rate fluctuations.

For patients who need to take obeticholic acid long-term, generic drugs undoubtedly provide a more economical option. However, patients should pay special attention to the source and quality of drugs when choosing, and ensure that the generic drugs they purchase meet relevant standards to ensure therapeutic efficacy and safety.

Reference materials:https://en.wikipedia.org/wiki/Obeticholic_acid