Pemetinib/pemetinib latest price trend in 2025

Pemigatinib is a new oral FGFR (fibroblast growth factor receptor) inhibitor, mainly used to treat certain cholangiocarcinomas with FGFR2 fusion or rearrangement mutations (especially intrahepatic cholangiocarcinoma). This type of tumor is clinically rare and has limited treatment options. The emergence of pemetinib provides a new molecularly targeted treatment option for these patients. The drug has been approved by drug regulatory agencies in multiple countries and has been included in treatment guidelines as a second-line and above treatment option. Its mechanism inhibits the proliferation and survival of tumor cells by blocking the FGFR pathway, and is highly targeted to patients with positive FGFR mutations.

In the Chinese market, pemetinib has been officially launched in the form of "pemetinib tablets". Currently, the common specifications are 4.5 mg 14 tablets and 9 mg 14 tablets. However, it has not yet entered the national medical insurance catalog, so the price is relatively high. According to market information, the price of a box of 4.5mg or 9mg pemetinib tablets is roughly between 20,000 yuan and 50,000 yuan. The price fluctuation is related to supply channels and regional differences. Overseas, such as the United States, the European Union and other countries, pemetinib is sold in the form of original drug, such as 13.5mg*14 tablets, and the price per box can be as high as 70,000 yuan or more. The specific price will also be affected by multiple factors such as exchange rate changes, taxes and transportation costs.

For patients with limited financial affordability, generic drugs have become another option. At present, in countries such as Laos and India, some pharmaceutical companies have launched generic versions. Among them, the more common product is Lucius Pharmaceuticals of Laos. The specification is 4.5mg*14 tablets. The price per box may be around 700 yuan, which is much lower than the original drug. Such generic drugs usually have the same active ingredients as the original drugs, but you still need to pay attention to whether they have strict international drug certification (such as FDA, EMA approval). Therefore, it is recommended to consult through channels and obtain professional advice from doctors when purchasing.

Reference materials:https://go.drugbank.com/drugs/DB15102