What is the market price of brigatinib/brigatinib in 2025?

Brigatinib/Brigatinib (Brigatinib) is a targeted drug used to treat non-small cell lung cancer (NSCLC) with ALK (anaplastic lymphoma kinase) fusion gene positivity. It is mainly intended for patients who are resistant to first-generation ALK inhibitors such as crizotinib. As a second-generation ALK tyrosine kinase inhibitor, brigatinib not only shows the ability to inhibit common drug-resistant mutations, but also shows strong penetration in the control of brain metastases, making it one of the preferred drugs for the clinical treatment of ALK-positive NSCLC. The indications of brigatinib have been approved by regulatory agencies in many countries and regions, including the State Food and Drug Administration of China. It is suitable for patients with ALK-positive advanced non-small cell lung cancer who have failed or are intolerant to crizotinib treatment.

In China, brigatinib has been officially launched as an original drug and has been included in the National Medical Insurance Category B Catalog, which means that patients can enjoy a certain percentage of drug cost reductions if they meet the conditions for medical insurance reimbursement, reducing the treatment burden. In terms of specifications and prices, the original brigatinib drug on the domestic market comes in various forms, including 30 mg × 14 tablets × 2 plates, 90 mg × 7 tablets or 7 tablets × 4 plates, and 180 mg × 7 tablets × 4 plates. The dosage can be adjusted according to the treatment stages of different patients. Although it has been included in medical insurance, the price of the original drug is still relatively high, and the price of each box may be close to 10,000 yuan. Especially the high-dose specifications will bring certain economic pressure during continued treatment.

In order to cope with the high cost of drugs, more and more patients are also paying attention to generic drug options in overseas markets. For example, the generic version of brigatinib produced in Laos has a significant price advantage. Taking 90mg × 30 tablets as an example, the price may be as low as about 500 yuan per box. Although the price is affordable, it needs to be purchased through legal channels while ensuring reliable sources and quality compliance.

Reference materials:https://www.alunbrig.com/