The cost of one course of gosatuzumab treatment

Gosatuzumab/Trodelvy (Trodelvy), as an innovative antibody-conjugated drug, has shown important value in the treatment of advanced breast cancer, especially for triple-negative breast cancer and some hormone receptor-positiveHER2-negative patients. However, the cost of this advanced therapy has been a major concern for patients and families. The treatment cost of gosatuzumab is not fixed and mainly depends on multiple factors such as the patient's weight, dosage cycle, dosage and treatment duration, so it cannot be generalized.

In general, the dosing schedule for gosatuzumab is two doses per cycle of 21 days. The dosage for each dose is calculated based on body weight, approximately 10 mg per kilogram. This means that a patient weighing 60 kg can take more than 600 mg in a single dose. Since the content of each bottle of gosatuzumab is usually 180 mg, multiple bottles need to be used in combination to meet the needs of one infusion. If treatment lasts for multiple cycles, the cost of a complete course of treatment may be higher.

In mainland China, gosatuzumab has been approved for marketing for a short time, so the price of the original drug is relatively high, probably around 10,000 yuan. The cost is slightly lower than overseas prices, but still high, and purchase assistance is required. Domestically, if Sartolizumab is approved and entered into the national medical insurance directory in the future, it is expected to significantly reduce the economic burden. It is worth noting that there are currently no generic drugs of gosatuzumab approved for marketing in the world, which means that the price lacks a competitive mechanism and is unlikely to drop significantly in the short term.

It should be pointed out that doctors will evaluate whether to continue using gosatuzumab based on the patient's treatment response. Some patients may discontinue treatment if the effect is not significant or the side effects are obvious after a few cycles, which will also affect the overall cost of treatment.

Reference materials:https://www.trodelvy.com/