How much does a box of Lorlatinib (lorlatinib) targeted drug cost? Price comparison at home and abroad and medical insurance reimbursement status

Lorlatinib (lorlatinib) is a third-generation ALK inhibitor used to treat ALK-positive non-small cell lung cancer. It has been officially launched in my country and has been included in the medical insurance catalog. Patients can purchase the drug directly at domestic hospitals or designated pharmacies, but even after reimbursement by medical insurance, the price is still relatively high. It is understood that the price of purchasing a box of Lorlatinib in China is about RMB 10,000 to 20,000. The actual out-of-pocket amount varies according to local medical insurance policies. It is recommended that patients consult the local hospital pharmacy to obtain the specific reimbursement ratio and amount.

In foreign markets, lorlatinib also has original drugs and multiple generic versions, and the price difference is obvious. Among them, the Turkish version of the original drug has attracted the attention of many patients due to its low price, which is about more than 7,000 yuan. The price of original research drugs in Hong Kong, China, is on the high side, with a box selling for about 30,000 yuan. Although they are all original drugs, there is a huge price gap due to regional differences.
In addition, there are also generic versions of lorlatinib (lorlatinib) from Laos and Bangladesh on the market, which are more affordable and generally range from more than 1,000 yuan to several thousand yuan. The active ingredients of these generic drugs are basically the same as those of the original drugs, and they are favored by many patients with limited economic conditions. However, when choosing to purchase overseas versions, patients need to pay attention to the formality of the channels and the authenticity of the drugs to ensure the safety of medication.
In general, lorlatinib (lorlatinib) is covered by medical insurance in China but the cost is still high, while overseas versions provide a variety of price options, especially generic drugs, which have more advantages in terms of cost performance.
Reference link: https://www.lorbrena.com/