The latest price and purchasing channels of levoketoconazole in 2025

Levoketoconazole is a cortisol synthesis inhibitor indicated for the treatment of endogenous hypercortisolism in adults with Cushing's syndrome. Intrinsic Cushing's syndrome is caused by chronic elevated cortisol exposure and is usually the result of a benign tumor of the pituitary gland. Levoketoconazole works by inhibiting a key step in cortisol synthesis. Levoketoconazole is the pure 2S, 4R enantiomer of ketoconazole, an approved steroidogenic inhibitor.

Levoketoconazole comes in tablet form and is taken by mouth twice daily with or without food. The doctor may start the patient on a low dose of levoketoconazole and then gradually increase the dose no more than once every 2-3 weeks. Levoketoconazole can control high levels of cortisol secondary to Cushing's syndrome but does not cure it. Continue taking levoketoconazole even if you feel well. Do not stop taking levoketoconazole without talking to your doctor.

Current common adverse reactions to levoketoconazole include nausea/vomiting, hypokalemia, bleeding/contusion, systemic hypertension, headache, liver injury, abnormal uterine bleeding, erythema, fatigue, abdominal pain/dyspepsia, arthritis, upper respiratory tract infection, myalgia, cardiac arrhythmia, back pain, insomnia/sleep disturbance, and peripheral edema.

The original drug of levoketoconazole is not on the market in China, and its price, medical insurance and other related information are not yet clear. Currently, the original drug of levoketoconazole sold overseas is 150mg*50 tablets per box, and the price may be more than 10,000 US dollars. The price is relatively expensive, and this price may be affected by exchange rates and other factors. For patients in need, please consult Yaode Medical Consultants for more information on overseas drug prices and related information.

Reference materials:https://medlineplus.gov/druginfo/meds/a622025.html