Domestic VS imported Apremilast/Apremilast tablets: What is the difference?

Apremilast/Apremilast, as an innovative immunomodulatory drug, is mainly used to treat plaque psoriasis, psoriatic arthritis (PSA) and related immune-mediated diseases. Since this drug entered the Chinese market, domestic and imported versions of Apremilast have gradually become important references for patients to choose. Although both have the same active ingredient, domestically produced and imported Apremilast differ in many aspects, including production, pricing, and drug accessibility.

First of all, the raw materials and production process of the drug are one of the most significant differences between domestically produced and imported Apremilast. Imported Apremilast is usually produced by internationally renowned pharmaceutical companies, and its production process is strictly regulated globally and complies with the drug standards of various countries. Imported versions generally go through a more complex quality control system to ensure the purity and stability of the drug. In addition, imported drugs usually need to go through a long international registration process to ensure that they comply with multinational drug safety regulations.

In contrast, domestically produced Apremilast is copied by domestic pharmaceutical companies based on the formula of international original drugs. Although it is produced in strict accordance with international standards in terms of quality, its production and inspection system may not be as complex as that of some large multinational companies. Domestic drugs have lower production costs and can usually bring more competitive prices, thereby reducing the financial burden on patients. Especially in our country, Apremilast has been included in the medical insurance directory, which makes the domestic version of Apremilast more accessible and affordable, especially for patients who need medication for a long time.

In terms of price, the advantage of domestic Apremilast is particularly obvious. The imported version is usually more expensive due to factors such as production costs, transportation fees and import duties, while the domestic version is relatively more affordable, making it more affordable for more patients. Especially under the coverage of medical insurance, patients’ out-of-pocket expenses for domestically produced Apremilast are greatly reduced, which is of great significance in my country’s medical environment and helps to increase the popularity and therapeutic effect of the drug.

Reference materials:https://go.drugbank.com/drugs/DB05676