Know all the prices of Pitobrutinib/Pitobrutinib, and you can budget for the drug in one article!

Pirtobrutinib is a selective Bruton's tyrosine kinase (BTK) inhibitor that is mainly used to treat relapsed or refractory diseases after multiple systemic therapies. Specifically, it is indicated for adults with relapsed or refractory mantle cell lymphoma (MCL) who have received at least two lines of systemic therapy, including BTK inhibitors, and who have received at least two prior lines of therapy. Treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) including BTK inhibitors and BCL-2 inhibitors. The establishment of these indications provides new treatment options for patients, especially those who do not respond to traditional treatments.

Pitobrutinib helps inhibit cancer cell proliferation and survival by selectively targetingBTK, thereby effectively controlling tumor growth. The drug has shown good safety and tolerability in clinical trials while improving patients' quality of life. This brings new hope to patients with relapsed or refractory lymphoma, especially when existing treatment options are limited.

Pitobrutinib has been marketed in China under the name Pitobrutinib, but it is not yet covered by medical insurance. A box of 100 mg tablets sold on the market, a total of 56 tablets, costs about 40,000 yuan, which is not cheap for many patients. In overseas markets, the original drug of pitobrutinib has two common specifications: European version and American version. For example, medicines with 30 tablets of 50mg and 60 tablets of 100mg may cost close to 100,000 yuan per box, which is relatively expensive, putting many families under huge financial pressure.

In addition, generic versions of pitobrutinib have also appeared in overseas markets. The ingredients of these generic drugs are basically the same as the original drugs, providing patients with some more reasonably priced options. For example, a generic drug produced by a Lao pharmaceutical factory with a specification of 50mg*30 tablets may be sold for more than 2,000 yuan per box. Although generic drugs are less expensive, patients still need to be careful when choosing to ensure the quality and safety of the drug they choose.

Reference materials:https://go.drugbank.com/drugs/DB17472