Is tazelast available in China? Latest developments and patient purchasing guide

Tazemetostat is the world's first EZH2 inhibitor. It is mainly used to treat adult patients with relapsed or refractory follicular lymphoma (R/R FL) (non-Hodgkin lymphoma) who are positive for EZH2 mutations and have received at least two previous systemic therapies. As an epigenetic targeted therapy drug, tazerestat blocks the growth of tumor cells by inhibiting the activity of EZH2 enzyme, thus providing a new treatment option.

On March 21, 2025, tazetostat was officially approved for marketing by the China National Medical Products Administration (NMPA), becoming the first EZH2 inhibitor in China. This approval provides a new treatment option for Chinese patients with follicular lymphoma, especially for relapsed or refractory cases after failure of standard therapies. The product name isTazverik/ Tazverik. However, due to its short time on the market, the specific selling price and medical insurance reimbursement of tazetostat are not yet clear, and patients need to wait for further official pricing and medical insurance negotiation results.

Although tazetostat has been approved in China, because it takes a certain amount of time for new drugs to enter the market, patients may still not be able to purchase it directly in domestic hospitals or pharmacies. For patients who are in urgent need of medication, the following ways to purchase medication can be considered:

1. Hospital clinical trials: Some domestic hospitals may be conducting clinical research on tazetostat. Eligible patients can consult the hospital and try to obtain the drug for free through clinical trial channels.

2. Overseas drug purchase: Tazetostat has been launched in many countries such as the United States, Europe and Japan, and patients can obtain the original drug through regular cross-border medical institutions or overseas drug purchase platforms. The price in the Japanese market is about more than 20,000 yuan (200mg, 56 tablets). Generic drugs in countries such as Laos may have more price advantages, with the price being about more than 4,000 yuan (200 mg, 56 pills); however, legal channels need to be chosen carefully.

Reference materials:https://www.tazverik.com/