How much does spaxentan/sparsentan cost for one day's use? where to buy

Sparsentan/Sparsentan is a new dual receptor antagonist mainly used to treat primary immunoglobulin A nephropathy (IgAN) and focal segmental glomerulosclerosis (FSGS). Due to its specific mechanism of action, the price of this drug in the global market is relatively high.

Currently, the recommended dose of sparsentane is 200 mg once daily, which can be adjusted to 400 mg daily based on tolerance 14 days after initial treatment. In the U.S. market, the drug has been approved by the FDA and is available as an original drug. Common specifications include 200mg 30 tablets and 400mg 30 tablets. According to the latest market information, the price of 400mg*30 tablets may be around 40,000 yuan, which is equivalent to the cost of taking 400mg per day of more than 1,000 yuan. If the patient takes the dosage of 200 mg once a day, the daily cost will be about 1,000 yuan.

In the European market, the price of Sparsentan is similar to that in the United States, and some countries may provide reimbursement by medical insurance. However, for patients not covered by medical insurance, the cost is still high, and the cost of a single daily dose may be more than 1 more than 1,000 yuan. In addition, there is less price information for the drug in some Asian countries, but it is usually not lower than the pricing in European and American markets.

It is worth noting that sparsentane has not yet been officially launched in China, so domestic patients cannot purchase the drug directly in pharmacies or hospitals. Some patients may choose to obtain drugs through cross-border medical treatment, overseas purchasing agents or international pharmacies. However, such drug purchasing methods may involve certain risks. Patients are advised to obtain drugs through formal channels and consult professional doctors to ensure drug safety.

In addition, generic drugs of sparsentan also exist in overseas markets, and some pharmaceutical factories in Laos or India may have produced similar generic drugs. For example, the 400mg*30 tablet version of Lucius Pharmaceuticals in Laos may be priced at more than 3,000 yuan, which is more advantageous than the original drug. If calculated as a generic drug, the cost of taking 400 mg per day is about RMB 100, which is much lower than the price of the original drug. However, the current efficacy and safety of generic drugs still need to be supported by more clinical data, and patients should be cautious when choosing and use them under the guidance of a doctor.

Reference materials:https://www.sparsentan.com/