2025 Latest Price and Purchase Channels for Irinotecan Hydrochloride Liposomal Injection (Onivyde)

Irinotecan Hydrochloride Liposomal Injection (Onivyde) is a prescription chemotherapy drug used to treat metastatic pancreatic cancer and is often used in combination with oxaliplatin, fluorouracil, and leucovorin as a first-line treatment option. In addition, Onivyde can also be used in combination with fluorouracil and leucovorin for patients whose disease has progressed after receiving gemcitabine.

Onivyde uses unique liposome technology to encapsulate irinotecan in tiny fat bubbles. This technology allows Onivyde to stay in the bloodstream longer and release the drug near pancreatic cancer, improving treatment effectiveness. After release, irinotecan will be converted into its active form SN-38 in the body, which can damage the DNA of cancer cells, prevent the proliferation of cancer cells, and ultimately lead to their death.

A recent study, NAPOLI 3, evaluated Onivyde in a new combination treatment regimen, NALIRIFOX. The results of the study showed that patients who received this new treatment lived about 2 months longer on average than those who received traditional standard treatments, further validating the potential of Onivyde in clinical treatment. .

Irinotecan Hydrochloride Liposomal InjectionThe original drug has been launched in China, but due to its short time on the market, it has not yet been included in the scope of medical insurance reimbursement. Common specifications include (10ml:43mg) injection dosage, each box may be sold for around RMB 8,000; while for the European version of irinotecan hydrochloride liposome injection sold overseas, the same specifications of the original drug may be sold for more than RMB 10,000 per box (the price may fluctuate due to exchange rates). In terms of purchasing channels, patients can obtain irinotecan hydrochloride liposome injection through hospitals. It is recommended that patients purchase and use this drug under the guidance of a doctor to ensure its safety and effectiveness. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.

Reference materials:https://go.drugbank.com/drugs/DB00762