What are the long-term side effects of Bituvi/Bikonprenol Tablets?

Bictegravir Sodium/Emtricitabine/Tenofovir Alafenamide Fumarate is a compound drug used to treat human immunodeficiency virus (HIV). Its main ingredients include bictegravir, emtricitabine and alenfamide. Patients may face some side effects when taking this drug long-term, although these may appear differently in different individuals.

Long-term use of this medication may have effects on the liver. Although most patients have normal liver function indicators during use, liver function still needs to be monitored regularly to prevent the risk of hepatitis or liver damage. In addition, As an antiviral ingredient, Tenofovir Alafenamide has low nephrotoxicity, but the possible decline in renal function caused by long-term use cannot be ignored, especially for patients with existing kidney disease.

Patients may experience metabolic changes during long-term use. For example, some patients may experience weight gain, elevated blood sugar, or abnormal lipid metabolism. These metabolic changes not only affect patients' quality of life but may also increase the risk of cardiovascular disease. Therefore, doctors often recommend that patients undergo regular metabolic monitoring.

In addition, mental health issues also need attention. Some patients may experience anxiety or depression during long-term antiviral treatment, which is closely related to long-term medication and the lifestyle changes it brings. Supportive psychological counseling may help cope with these problems.

In terms of the immune system, although the drug can effectively suppressHIV, long-term use may cause changes in the immune response of some patients and increase the risk of infection with other pathogens. Therefore, patients should maintain good hygiene habits and undergo regular health examinations while using the drug.

Reference materials:https://www.ema.europa.eu/en/medicines/human/EPAR/biktarvy