What are the ingredients of Biktarvy?

The ingredients of Biktarvy tablets (Biktarvy) include the following three active ingredients:

1.Bictegravir (Bictegravir): Bictegravir is an integrase inhibitor. Its role is to block the integrase of human immunodeficiency virus (HIV), which is the process by which the virus integrates its genetic material (RNA) into the host cell's DNA in the host cell. By inhibiting integrase activity, bicviramib blocks the replication and spread of HIV viruses.

2.Entecavir (Emtricitabine): Entecavir is a nucleoside reverse transcriptase inhibitor. It interferes with the reverse transcription process of the HIV virus and prevents the virus from transcribing its RNA into DNA. Entecavir blocks a key step in viral replication, thereby inhibiting the spread of HIV and further infection.

3.Tenofovir (Tenofovir Alafenamide): Tenofovir is a nucleoside reverse transcriptase inhibitor. It works synergistically with entecavir to prevent the HIV virus from transcribing its RNA into DNA by inhibiting the activity of viral reverse transcriptase. Tenofovir is converted into an active metabolite in the body, with better tissue distribution and lower systemic exposure, thus providing a lower risk of side effects.

These three active ingredients work together to form the therapeutic effect of Bikern Prenol Tablets. Bicviramib inhibits integrase, while entecavir and tenofovir block the reverse transcription process, jointly inhibiting the replication and spread of HIV virus, helping to control viral infection and maintain the patient's immune function.

Bikernoprenol tablets have been launched in China and have been included in medical insurance. Patients can purchase them domestically. The original drug is mainly imported in China, and the price is around 1,500 yuan. Please consult the local hospital pharmacy or medical insurance bureau for specific prices and reimbursement conditions. The cheaper ones abroad are generic drugs, mainly Indian generic drugs. The price is about 450yuan, and the ingredients of original drugs and generic drugs are basically the same.