Which generation of targeted drugs does Platinib/Pujihua belong to? What is its market positioning?
Pralsetinib (Pralsetinib) belongs to a new generation of RET inhibitors. RET gene fusions are oncogenic mutations that cause a variety of cancers, and are particularly common in patients with non-small cell lung cancer (NSCLC) and thyroid cancer. The emergence of platinib has filled the previous gap in targeted treatments for RET mutations and has become an innovative drug in this field. As a targeted drug, platinib has advantages in drug design. Compared with early targeted drugs, platinib can target RET gene fusion more accurately and has a stronger inhibitory effect on tumor cells caused by this mutation.

Traditional targeted drugs are usually only effective against a subset of tumor cells, while Platinib can effectively block the signaling pathways of cancer cells and inhibit their growth and spread by specifically targeting RET gene mutations. Such precise treatment enables Platinib to have higher efficacy and lower risk of side effects in clinical applications.
In terms of market positioning, Platinib is mainly targeted at cancer patients with positive RET gene mutations, especially those with non-small cell lung cancer and thyroid cancer for whom traditional treatments are ineffective. Its launch fills the treatment gap for RET gene mutations and provides an effective treatment option for these patients. Platinib is considered a "targeted revolutionary" drug that is not only suitable for patients with advanced cancer that has progressed, but also has a good therapeutic effect on some early-stage tumors.
Platinib’s market positioning can be said to be very precise, and its targeted treatment mechanism is in line with the development trend of precision medicine. Globally, more and more patients have achieved remarkable results after receiving targeted therapy, which makes Platinib's application prospects in the field of cancer treatment very broad. As the understanding of RET gene mutations continues to deepen, the market demand for platinib is also gradually growing.
Keyword tags: pralsetinib,Pralsetinib, RET gene mutation, targeted therapy, non-small cell lung cancer, thyroid cancer, precision medicine, cancer treatment
Reference: https://gavreto.com/
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