What are the requirements for the storage conditions of selumetinib/coceyu?

Selumetinib is usually used for chronic or long-term treatment of children and adults with neurofibromatosis (NF1). Therefore, good storage conditions are the basis for ensuring efficacy and safety.

1. Temperature management: Selumetinib should be kept sealed and stored in an environment not exceeding30°C. Large temperature fluctuations or high-temperature environments may reduce the stability and effectiveness of drugs. Be especially careful not to store medications in areas with moisture, high temperatures, or direct sunlight, such as in the bathroom, kitchen, or car. Overseas guidelines also recommend that oral anti-tumor drugs be stored in a constant temperature, dry, and dark environment to ensure that the drugs maintain stable efficacy throughout the entire treatment cycle.

2. Packaging and container requirements: Medications should always be kept in their original containers and kept sealed. After opening, try to use it within the specified time and do not transfer it to other containers at will to prevent moisture or contamination. The original packaging usually has a light-proof design, which can reduce the degradation of pharmaceutical ingredients by light. When patients store their medications at home, they should keep their medications in a safe place out of the reach of children to avoid accidental ingestion or contact.

3. Precautions for use: After opening, please use it in accordance with the instructions and doctor's advice. Do not divide doses at will or mix them into other drug containers. If there is any precipitation, discoloration, odor or abnormal particles in the medicine, you should stop using it immediately and consult a pharmacist or doctor. The drug instructions suggest that for patients who have long-term use of selumetinib, checking the appearance of the drug before taking the drug each time can reduce adverse reactions or reduced efficacy caused by drug deterioration.

4. Travel and carrying: When patients go out or travel, they should put the medicine in a sealed bag or thermal insulation bag to ensure a constant temperature of the medicine. Do not expose the medicine directly to the sun or place it with high-temperature items, such as in a car or in a backpack, as this may cause the medicine to degrade.

In short, rational storage of selumetinib can not only ensure drug stability, but also reduce unnecessary waste and safety risks. Patients should strictly abide by medical instructions, packaging requirements and temperature control measures, while paying attention to the appearance and expiration date of the drug.

Keyword tags: Selumetinib storage conditions, Selumetinib storage method, NF1 oral drug management, oral antineoplastic drug stability, safe drug use, home medication guide, long-term medication precautions

References：https://www.medicines.org.uk/emc/product/12948/smpc