What is the price of Upadacitinib and how do patients choose it?

Upadacitinib (Upadacitinib) is an oral small molecule targeted drug that has been widely used in the field of autoimmune diseases in recent years. It has been officially launched in China and has been included in the national medical insurance system. For most patients, price is one of the important factors in deciding whether to take medication regularly over the long term. Judging from the domestic market situation, the common specification of upadatinib is 15 mg × 28 tablets, and the public price before medical insurance reimbursement is approximately RMB 2,000. The actual out-of-pocket cost will vary depending on regional medical insurance policies, hospital levels, and individual reimbursement ratios.

Compared with the domestic market, the price of overseas original research upadatinib is significantly higher. In regions such as Europe, original research versions are usually sold in the same dosage specifications, and the price of a single box may be more than 20,000 yuan. This is mainly related to the local drug pricing system, patent protection and distribution costs. Therefore, for patients who do not have overseas medical channels or commercial insurance support, the financial burden of directly choosing overseas original drugs is relatively heavy.

In recent years, some generic versions have gradually entered patients' horizons. For example, the generic version of upadatinib produced by Lucius, Laos, has the same main active ingredients as the original drug and is relatively affordable. Each box sells for about 500 yuan. For patients who require long-term medication and are under greater financial pressure, such generic versions may become an alternative that can be considered after physician evaluation.

In the actual selection process, patients with rheumatoid arthritis (RA) should not only use price as the only judgment criterion, but also need to comprehensively consider the compliance of the drug source, quality stability, drug safety, and whether it is easy to obtain in the long term. At the same time, it is recommended to give priority to formulating a medication plan under the guidance of a rheumatology department or dermatologist to avoid affecting the continuity of treatment by changing sources or dosage forms on your own.

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Reference materials:https://www.ncbi.nlm.nih.gov/books/NBK572088/