Detailed description of domestic price of Pemigatinib and reference cost of drug purchase

Pemigatinib is an oral FGFR (fibroblast growth factor receptor) inhibitor mainly used to treat patients with cholangiocarcinoma with FGFR2 rearrangements or fusions. In the domestic market, pemetinib tablets are already on the market, but have not yet been included in the scope of medical insurance reimbursement, which means that patients need to bear all the drug costs themselves. Common specifications in the domestic market include 4.5mg14 tablets and 9mg14 tablets. The price per box ranges from 2 10,000 to 5 Between RMB 10,000 and RMB 10,000, the specific cost will vary slightly depending on the region and pharmacy.

In overseas markets, the price of the original drug pemetinib is higher. For example, 13.5mg*14 tablet specifications, the price per box may be as high as 7 around 10,000 yuan (may change due to exchange rate fluctuations). Overseas purchases usually need to be completed through legal prescription and pharmacy channels, and combined with local import and customs declaration regulations to ensure drug quality and medication safety. The high price of original drugs may put certain financial pressure on patients who take the drugs for a long time.

In order to reduce the cost of medication, generic versions of pemetinib have been launched in some overseas markets. Generic drugs are basically the same as the original drugs in terms of ingredients and efficacy, but are significantly cheaper. For example, the 4.5mg*14 tablets produced by Lucius Pharmaceuticals in Laos are priced at approximately 700 multiple RMB per box (which may change slightly due to exchange rate fluctuations), providing a viable option for patients with limited financial ability. When using generic drugs, you still need to follow doctor's guidance and purchase drugs through formal channels to ensure the safety of treatment.

Overall, the price difference of pemetinib at home and abroad is large. If domestic patients choose original drugs, they will have to bear higher out-of-pocket costs, while overseas generic drugs provide an economically feasible alternative. During the drug purchase process, patients should choose regular channels to purchase based on their own financial situation, treatment plan and doctor's advice, and closely monitor treatment effects and adverse reactions to ensure a safe and effective medication experience.

Keyword tag:

FGFR2Inhibitors, cholangiocarcinoma, targeted therapy, drug prices, medical insurance policies, generic drugs, economic burden, drug safety, treatment continuity

Reference materials:https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/213736s002lbl.pdf