Analysis of whether methylcobalamin injection (Rozebalamin) is effective in treating tinnitus and improving auditory nerve damage

Methylcobalamin injection (Rozebalamin) is a drug newly developed by Japan Eisai for the treatment of amyotrophic lateral sclerosis (ALS). Its main mechanism of action is to promote nerve regeneration and repair by supplementing active vitamin B12 (methylcobalamin). In nervous system injuries, methylcobalamin can participate in the synthesis of DNA and RNA, enhance myelin repair, thereby improving nerve conduction function, and has a certain protective effect on damage to motor nerves and some sensory nerves.

Regarding the therapeutic effect of tinnitus, current clinical studies and patient observations show that methylcobalamin injection may bring some relief to some patients with tinnitus. This is mainly because tinnitus is often related to auditory nerve dysfunction or peripheral nerve damage, and methylcobalamin helps relieve tinnitus symptoms caused by nerve damage by promoting nerve repair and improving nerve metabolism. However, this effect is not effective in all patients, there are individual differences in efficacy, and it often takes several weeks to months of continued medication before significant improvement is observed.

In terms of improving auditory nerve damage, methylcobalamin injection helps restore nerve conduction speed and function by promoting myelin regeneration and neuronal metabolic activity. This has a certain auxiliary effect on hearing loss or tinnitus caused by neurodegenerative diseases or mild to moderate nerve damage. In clinical use, doctors usually combine the patient's neurological function assessment and hearing test results to formulate an individualized medication plan to maximize the improvement of auditory nerve function, while monitoring possible adverse reactions during treatment.

In general, methylcobalamin injection has scientific basis for repairing nerve damage and may bring some improvement to tinnitus and auditory nerve damage. However, its efficacy has individual differences and cannot replace other professional otology or neurological treatments. During use, patients should follow the physician's guidance, combine regular neurological function and hearing assessments, and scientifically manage the course and dosage to achieve the best therapeutic effect.

Keyword tag:

Methylcobalamin injection, Rozebalamin, amyotrophic lateral sclerosis, ALS, neuralgia, mechanism of action, efficacy, safety, vitaminsB12

Reference materials:https://en.wikipedia.org/wiki/Mecobalamin