Dosage and method of use of nintedanib/Vigat

Nintedanib (Nintedanib) is an oral drug commonly used to treat idiopathic pulmonary fibrosis (IPF), fibrosing interstitial lung disease (ILD), systemic sclerosis-related interstitial lung disease and other diseases related to pulmonary fibrosis. The dosage and method of administration of nintedanib will vary depending on the treatment plan.

1. Recommended dose: When nintedanib is used to treat idiopathic pulmonary fibrosis (IPF), fibrosing interstitial lung disease (ILD) and systemic sclerosis-related interstitial lung disease, the standard dose is 150 mg orally twice daily. The interval between each dose is about 12 hours.

2. Treatment of missed doses: If a dose is missed, the patient should take the next dose at the next scheduled time and should not make up for the missed dose. Avoid dosing intervals that are too short or exceeding the maximum recommended dose.

3. Maximum dose limit: The maximum daily dose should not exceed300 mg. Taking any more than this dose may increase the risk of side effects.

4. Medication method: Nintedanib should be taken with food to reduce gastrointestinal discomfort. Patients can choose to take it with breakfast or dinner to ensure absorption of the drug and reduce stomach upset.

5. Long-term use: Nintedanib is suitable for long-term use, especially for the management of chronic diseases such as pulmonary fibrosis. Patients should seek medical treatment regularly and have liver and kidney function monitored.

6. Individualized adjustment: Individual differences of patients (such as age, liver and kidney function, etc.) may require dosage adjustment under the guidance of a doctor. The dose may need to be reduced in the elderly and patients with hepatic impairment.

7. Mistaken medication: If the patient accidentally takes more than the recommended dose of nintedanib, he should contact his doctor in time to evaluate whether emergency measures are needed.

In summary, the standard use of nintedanib is 150 mg orally twice dailywith a maximum daily dose of 300 mg. Patients should strictly follow their doctor's recommendations, avoid adjusting the dosage on their own, and ensure they take their medications on time. If you miss a dose, take it on time for your next dose and do not make up for the missed dose.

Keyword tags: nintedanib, Vegat, Nintedanib, dosage, pulmonary fibrosis, treatment method, missed dose, dosing interval

Reference materials:https://go.drugbank.com/drugs/DB09079