Effects and medication recommendations of Methylcobalamin Injection (Rozebalamin) in the treatment of lumbar disc herniation

Methylcobalamin injection (Rozebalamin) is a newly developed drug for the treatment of amyotrophic lateral sclerosis (ALS, ALS). Its main mechanism of action is to exert the potential of neuroprotection and promotion of nerve regeneration through high doses of methylcobalamin. Although its application in ALS has been strictly clinically verified, its neuroprotective effect can also be used to relieve symptoms caused by nerve compression in the adjuvant treatment of lumbar disc herniation. Lumbar disc herniation is often accompanied by nerve root compression, resulting in radiating pain, numbness and decreased muscle strength in the lower limbs. Rozebalamin can improve nerve conduction function and provide auxiliary support for conservative treatment.

In clinical practice for lumbar disc herniation, Rozebalamin injection can be used in combination with physical therapy, rehabilitation training and non-steroidal anti-inflammatory drugs to improve nerve function and relieve pain. Although its main research and development goal is ALS, research and clinical observations show that high-dose methylcobalamin still has certain value in promoting the recovery of peripheral nerves and compressed nerves, and is especially suitable for patients with mild to moderate symptoms and no indications for surgery.

In terms of medication, Rozebalamin injection can be administered by intramuscular injection or intravenous infusion, and the usual dose is 500 per day––1000micrograms, the course of treatment is 2 to 4 weeks, and can be extended appropriately according to the improvement of symptoms. Initial use should be performed in a medical facility to observe tolerability and potential adverse reactions, such as mild pain at the injection site or allergic reactions. During the treatment process, the dose should be dynamically adjusted based on neurological function assessment and pain scores to ensure both safety and efficacy.

In general, although Rozebalamin is a new drug developed specifically for ALS, it can still play a certain neuroprotective role in the auxiliary treatment of lumbar disc herniation, helping to relieve radiating pain and numbness in the lower limbs and promoting the recovery of neurological function. Clinical use should be combined with rehabilitation training and symptomatic drugs, and follow the principles of individualized medication and regular monitoring to achieve the best results in symptom improvement and functional recovery.

Keyword tags: Methylcobalamin injection, lumbar disc herniation, nerve protection, adjuvant treatment, medication suggestions

Reference materials:https://pubmed.ncbi.nlm.nih.gov/?term=mecobalamin