When is the best time to take Nintedanib/Vigat and what is the taking time?

Nintedanib (Nintedanib) is a commonly used drug to treat lung diseases, especially idiopathic pulmonary fibrosis (IPF) , interstitial lung disease (ILD) and other related diseases. As a tyrosine kinase inhibitor, nintedanib reduces the occurrence and progression of the fibrosis process by inhibiting specific enzymes, thereby effectively slowing the deterioration of lung function. In order to ensure the best effect and minimal side effects of the drug, reasonable time and method of taking it are crucial.

The recommended dose of nintedanib is taken by mouth twice daily with food. Food not only helps slow down the absorption of drugs and reduces irritation to the gastrointestinal tract, but also enhances the bioavailability of drugs. Doctors usually recommend that patients take medication at a fixed time each day, such as once in the morning and once in the evening. This not only helps patients form regular medication habits, but also helps the drug maintain a stable concentration in the body.

Concerning the choice of taking time, it is recommended that the interval between two doses is approximately 12 hours. This can help maintain the drug concentration within the range required for treatment and ensure maximum drug efficacy. For some patients, especially those who have work or other daily activities, they can choose to take the medicine separately in the morning and evening to ensure that the effect of the medicine in the body is more lasting and stable.

In addition to the choice of medication time, patients also need to pay attention to the relationship between medication and diet. Although nintedanib can be taken with food, it is best to avoid taking it on an empty stomach. On an empty stomach, medications may cause greater irritation to the stomach, causing uncomfortable symptoms such as stomach pain or nausea. Food intake can not only relieve these discomforts, but also improve the absorption efficiency of drugs and help patients obtain better therapeutic effects.

Generally speaking, the best time to take nintedanib is twice a day, once in the morning and once in the evening, and it is recommended to take it with food to ensure effective absorption of the drug and reduce side effects. Patients need to follow the doctor's guidance during medication, maintain stable medication habits, and undergo regular health checkups to ensure optimal treatment effects.

Reference materials:https://www.ema.europa.eu/en/medicines/human/EPAR/ofev