Crizotinib price and reference after medical insurance reimbursement in 2026
As one of the first ALK/ROS1 targeted therapies to be marketed in China, Crizotinib has been included in the medical insurance catalog, which means that patients can enjoy the medical insurance reimbursement policy when using it, thus reducing their financial burden. The actual out-of-pocket amount paid by patients will vary depending on the specific implementation conditions of different regions and hospitals. Therefore, it is recommended to consult the local hospital pharmacy before purchasing drugs to obtain the most accurate medical insurance reimbursement price information.
In the domestic market, crizotinib mainly comes in two specifications: 250mg 60 tablets and 200mg 60 tablets. The retail price of each box of medicines may exceed 10,000 yuan. After medical insurance reimbursement, the patient's out-of-pocket portion will be reduced based on local medical insurance policies and reimbursement ratios. For patients undergoing long-term treatment, medical insurance support has significantly reduced the financial pressure, allowing more patients who meet the indications to continue to use crizotinib for targeted therapy, thereby effectively controlling the disease.

In overseas markets, the price of the original crizotinib drug is also high, with each box usually selling for more than 10,000 yuan, and the price will be affected by exchange rate fluctuations and regional policies. For patients who need to purchase drugs across borders, the cost is high, and issues such as drug transportation, customs clearance and reliability also need to be considered. Therefore, overseas original drugs are mainly suitable for patients who purchase them through formal channels to ensure drug quality and treatment safety.
In order to reduce the economic burden, lower-priced versions of generic drugs have appeared in some overseas markets. The ingredients of these generic drugs are basically the same as the original drugs. Taking the specifications of 250mg*60 tablets produced by Lucius Pharmaceuticals in Laos as an example, the price per box is only more than 1,000 yuan (may fluctuate slightly due to exchange rates). This generic drug provides a feasible alternative for patients with limited financial conditions or self-payment. At the same time, while ensuring the efficacy, it allows patients to continue to receive targeted therapy to control their disease and improve their quality of life.
Reference:https://en.wikipedia.org/wiki/Crizotinib
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