Safety assessment and recommendations for long-term use of Lemborexant

Lemborexant has been widely used as a drug for the treatment of insomnia. Safety issues during long-term use are important topics that patients and doctors need to pay attention to. Leborexan has a good safety profile, but like all medications, there may be risks with long-term use.

First of all, the most common side effects of leborexan are mild drowsiness and dizziness. These side effects usually occur in the early stages of taking the drug. As the body adapts to the drug, these symptoms tend to reduce or disappear. With long-term use, patients need to watch for symptoms such as persistent drowsiness, difficulty concentrating, or memory loss. If these problems occur, it is recommended to communicate with the doctor in time to adjust the medication plan or change medications.

Secondly, although leborexan is not as likely to cause dependence and abuse problems as some traditional sleeping pills, long-term use may make some patients dependent on the drug. In order to reduce this risk, doctors usually recommend that patients follow a reasonable medication cycle and avoid long-term continuous use of leborexan. If a patient relies on medication to fall asleep for a long time, he or she may need other ways to improve sleep quality, such as non-pharmacological treatments such as cognitive behavioral therapy.

Furthermore, the hepatic metabolism characteristics of leborexan mean that changes in liver function need to be paid attention to during long-term use. Especially for patients with existing liver function abnormalities, regular liver function checks are required during long-term use. If signs of liver impairment occur, the drug dose may need to be reduced or discontinued.

In addition, although leborexan has fewer side effects and less dependence than other sedative drugs, caution is still required during long-term use. Patients should be regularly evaluated and monitored by doctors during treatment to ensure medication safety. For elderly patients, especially those with multiple underlying diseases, extra caution should be exercised when using leborexan, and the dose should be adjusted if necessary.

Reference materials:https://go.drugbank.com/drugs/DB11951