What generic drugs of serputinib/serpatinib are currently on the market?

Selpercatinib is a targeted drug used to treat RET-driven non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC; thyroid cancer) and other RET fusion-positive solid tumors. Since the launch of the original drug, the market demand for seputinib has gradually increased, which has also led to the development and launch of related generic drugs.

Currently, pharmaceutical companies in many countries and regions have begun to produce and market generic versions of seputinib. Although the ingredients of these generic drugs are consistent with the original drugs and are mainly used to treat RET fusion-positive non-small cell lung cancer and medullary thyroid cancer, they may differ in terms of production specifications, pricing, and patient availability.

In countries such as Bangladesh and Laos, multiple pharmaceutical manufacturers have launched generic versions of seprotinib. For example, the generic version of Seputinib produced by Lusious Pharmaceuticals in Laos has a specification of 40mg*120 pills per box, and the price is about more than 2,000 yuan, which has a clear cost advantage compared with the price of the original drug. Bangladesh's Himalaya Pharmaceuticals is also one of the major manufacturers. The quality of its generic drugs is consistent with the original drugs, and it also provides a relatively reasonable price range, which is especially favored by patients.

Regarding the quality assurance of these generic drugs, relevant companies stated that they follow international drug production standards to ensure that they are highly consistent with the original drugs in terms of active ingredient content, dissolution rate and therapeutic effect. Since the production process of these generic drugs is similar to that of the original drugs, patients can use them with confidence. However, despite this, due to differences in production processes, regulatory enforcement, quality control, etc. between some generic drug manufacturing companies, patients still need to consult a doctor or pharmacist in detail before use to ensure that they choose a proven and reliable brand.

Reference:https://en.wikipedia.org/wiki/Selpercatinib