How should fostatinib/fotantinib be stored?

Fostamatinib is an oral small molecule kinase inhibitor mainly used to treat adult patients with chronic immune thrombocytopenia (ITP). As part of the long-term management of chronic disease, the storage conditions of medications are important to ensure efficacy and safety. Fostatinib tablets should be stored at room temperature between 20°C and 25°C, with some temperature fluctuation between 15°C and 30°C allowed. This storage range helps maintain the stability of the chemical components of the drug and prevents it from degrading or becoming ineffective in high or low temperature environments. For patients, understanding and adhering to proper storage requirements can ensure they get the desired effect every time they take their medication.

The fostatinib vial contains two desiccant canisters, which are an important part of the drug packaging. The function of the desiccant is to absorb the moisture inside the medicine bottle and prevent the tablets from becoming damp, which may cause deterioration, adhesion or solubility changes. When using, be careful not to remove the desiccant or directly contact the tablets, so as to maintain the stability and effectiveness of the medicine. Moisture in drugs may reduce the bioavailability of active ingredients, thereby affecting platelet recovery speed and clinical efficacy. In a home environment, patients should avoid placing medicines in humid environments, such as bathrooms or kitchens near water sources, and should also avoid prolonged exposure to direct sunlight or high temperatures. These factors may affect the quality of medicines.

In addition, fostatinib should be stored in a safe place out of reach of children to prevent potential risks from accidental ingestion. ITP patients usually need to take fostatinib for a long time. Scientific storage and management not only contribute to drug safety, but also help to improve medication compliance and treatment continuity. Proper storage of medicines also ensures the effectiveness of home backup medicines and avoids interruption of treatment or unnecessary medical expenses due to damaged medicines.

Reference: https://www.tavalisse.com/whattoexpect