Lenvatinib/Lenvatinib (Lenvima) side effects and safe medication tips

Lenvatinib/Lenvatinib (Lenvatinib), as a targeted therapy drug, has shown significant efficacy in the treatment of cancer (renal cell carcinoma, hepatocellular carcinoma, thyroid cancer, and endometrial cancer), but like all drugs, it may also cause certain side effects. Therefore, during treatment with lenvatinib, patients need to pay special attention to some potential side effects and use the medication rationally under the guidance of a doctor.

Common side effects include high blood pressure, fatigue, decreased appetite, weight loss, nausea, diarrhea, and hand-foot syndrome (skin peeling or pain on the hands and feet). These side effects are usually temporary and can be relieved with certain dosage adjustments and symptomatic treatment. However, if symptoms are severe or persist, patients should promptly report to their physician so that dose adjustment or other treatment can be performed.

Hypertension is the most common side effect of lenvatinib treatment. High blood pressure can cause serious cardiovascular problems, so patients should have their blood pressure monitored regularly during treatment. If blood pressure is elevated, steps should be taken to intervene, possibly with antihypertensive medications if necessary.

Impaired liver function is also a problem that requires vigilance during lenvatinib treatment. Some patients may experience elevated liver enzymes during treatment, especially AST (aspartate aminotransferase) and ALT (alanine aminotransferase). Therefore, doctors usually recommend regular liver function tests when patients are taking lenvatinib. If abnormalities are found, the medication should be stopped immediately and appropriate treatment should be carried out.

In addition to the above side effects, lenvatinib may also affect gastrointestinal function, such as causing nausea, vomiting, abdominal pain or diarrhea. Patients can reduce gastrointestinal discomfort by dividing meals, avoiding greasy foods, and arranging proper rest after meals. If symptoms are severe, patients should seek medical treatment promptly.

Reference materials:https://www.lenvima.com/