How to safely take avatrombopag (Su Kexin) after missing a dose

Avatrombopag (trade name: Avatrombopag) is an oral thrombopoietic drug commonly used to treat chronic liver disease-related thrombocytopenia or chronic immune thrombocytopenia. This medicine needs to be taken strictly in accordance with the dosage and time prescribed by the doctor to maintain a stable effect in the body. If a dose is missed, care must be taken to prevent excessive platelet levels or fluctuations from affecting the efficacy.

If the patient finds that he has missed a dose, he should first confirm the time until the next dose: if the time until the next dose is long (more than 12 hours), he can take the dose as soon as possible However, if it is close to the time for the next dose (less than 12 hours), you should skip the missed dose and take the next dose at the original time. Do not "double dose" to make up for the missed dose. Overdose of medication may cause excessive elevation of platelets and increase the risk of blood clots. Patients with combined liver disease or cardiovascular disease need to be more cautious.

Patients do not need to panic or adjust their regimen in the short term after missing a dose. The drug effect of avatrombopag lasts relatively long, and missing a small amount will generally not cause a sudden drop in platelets immediately. If symptoms such as obvious bleeding tendency, increased subcutaneous ecchymosis, or dizziness and fatigue occur after missing a dose, you should contact your doctor or go to the hospital for platelet monitoring in time so that subsequent dosage can be adjusted based on the test results.

In order to avoid missing doses, it is recommended that patients take medication at a fixed time and use medication recording or reminder tools, such as mobile phone alarm clocks, pill box timing functions, etc. Long-term regular medication is the key to maintaining the efficacy of avatrombopag. If you miss doses frequently or have large platelet fluctuations, be sure to communicate with your attending doctor, who will decide whether to adjust the dose or change the treatment plan to ensure the safety and stability of the treatment.

Reference materials:https://www.drugs.com/