What are the contraindications when using 0.01% atropine sulfate eye drops (EIKANCE)

0.01% atropine sulfate eye drops (EIKANCE), as a low-concentration anticholinergic drug, has been widely studied to control the progression of myopia in children. Although the side effects of low-concentration atropine are relatively mild, it is still a prescription drug. Understanding its contraindications and precautions before use is crucial to ensure safety.

First, this drug should not be used in patients with a known history of allergy to atropine or other anticholinergic drugs. This group of people may have adverse reactions to drug ingredients, including eye irritation, redness and swelling, or systemic allergic-like reactions, so they need to inquire about their allergy history in advance. Children with a history of skin drug allergies should also have their doctor confirm safety.

Secondly, people with certain eye diseases need to avoid or use it with caution. For example, in patients with acute angle-closure glaucoma or narrow anterior chamber angle, atropine may cause pupil dilation and increase the risk of intraocular pressure; in patients with intraocular inflammation, corneal damage, and severe dry eye, atropine may further affect the stability of the tear film or aggravate symptoms. In these cases, doctors often choose other myopia control strategies, such as OK lenses or optical defocus lenses.

Third, people with systemic diseases also need special attention. Some children with cardiovascular disease, thyroid dysfunction, severe asthma, or autonomic nervous system disorders may be more sensitive to anticholinergic drugs and should be evaluated under the guidance of a doctor to determine whether they are suitable for use. In addition, underweight children, those who are highly sensitive to light, and those who use other drugs that inhibit the cholinergic system should also have their doctors determine the risks in advance.

During use, if obvious photophobia, persistent blurred vision, symptoms of increased intraocular pressure, headache, or unexplained visual changes occur, you should stop using it immediately and seek medical advice. Although 0.01% has a low concentration and generally does not cause significant regulatory paralysis, individual differences may still cause discomfort.

Reference: https://www.eikance.com.au/